CHMP2A

Across TCGA patient cohorts, CHMP2A protein abundance is significantly associated with the RNA expression of many other genes, with 8,762 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CHMP2A-associated genes across cancer lineages are NDUFA3, ZNF587, and LENG1. Each is linked with CHMP2A in more than 4 cancer types. Because this analysis shows association rather than direction, both CHMP2A-to-partner and partner-to-CHMP2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHMP2A versus NDUFA3 in UCEC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHMP2A→partner) and Y-score (partner→CHMP2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NDUFA3 →	+0.586	+0.214	<.001	.001	3	5
BRCA	ZNF587 →	+0.857	+0.353	<.001	<.001	3	5
UCEC	LENG1 →	+0.933	+0.241	<.001	<.001	3	4
BRCA	TMC4 →	+0.994	+0.476	<.001	<.001	3	4
UCEC	ZNF524 →	+1.153	+0.218	<.001	<.001	3	4
LSCC	ZSCAN22 →	+0.411	+0.351	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,762 associations by consensus.

CHMP2A vs NDUFA3 — UCEC

Explore this scatter interactively →