CHMP1B2P

Across TCGA pan-cancer cohorts, CHMP1B2P RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated CHMP1B2P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CHMP1B2P RNA is associated with better overall survival. In most high-consensus cancer types, elevated CHMP1B2P expression acts as an unfavorable survival marker, although some lineages such as HNSC and MESO show a favorable association.

HNSC, MESO, and LIHC are the cancer types where CHMP1B2P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	II,III,IV	0.454	0.221	<.001	85	view →
MESO	OS	Median	III,IV	0.711	0.425	.001	35	view →
LIHC	DFS	Quartile	All	0.310	0.477	.001	26	view →
COAD	DFS	Quartile	All	0.692	0.843	<.001	24	view →
OV	DFS	Quartile	All	0.486	0.588	.016	14	view →
TGCT	DFS	Quartile	All	0.944	0.644	.001	14	view →
ACC	OS	Quartile	All	1.000	0.504	.012	10	view →
PRAD	DFS	Tertile	All	0.964	0.913	.005	10	view →
READ	OS	Quartile	All	0.736	0.312	.010	9	view →
DLBC	DFS	Median	III,IV	1.000	0.146	.017	7	view →
LAML	DFS	Median	All	0.248	0.507	.031	6	view →
BLCA	OS	Median	All	0.520	0.378	.014	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

CHMP1B2P–HNSC (OS)

Open the HNSC breakdown →