CHMP1B2P

Across TCGA pan-cancer cohorts, CHMP1B2P RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of CHMP1B2P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CHMP1B2P RNA is repressed in tumor relative to normal tissue. In most cancer types CHMP1B2P is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and STAD are the cancer types where CHMP1B2P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CHMP1B2P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	II,III,IV	−0.624	<.001	12	view →
KICH	Male	II,III,IV	−0.853	<.001	9	view →
STAD	All	All	+0.394	.006	6	view →
THCA	Female	All	−0.508	<.001	4	view →
READ	All	All	−0.273	.001	3	view →
KIRP	Male	All	−0.266	.008	3	view →
CHOL	All	All	+0.907	.003	2	view →
UCEC	All	All	+0.651	.019	2	view →
LUSC	All	III,IV	−0.130	.048	1	view →
LIHC	All	All	+0.106	.021	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

CHMP1B2P–KIRC

Open the KIRC breakdown →