Across TCGA patient cohorts, CHL1-AS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,117 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CHL1-AS2-associated GO terms across cancer lineages are Proton motive force-driven ATP synthesis, Regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, and ATP biosynthetic process. Each is linked with CHL1-AS2 in more than 13 cancer types. Because this analysis shows association rather than direction, both CHL1-AS2-to-partner and partner-to-CHL1-AS2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHL1-AS2→partner) and Y-score (partner→CHL1-AS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRP	Proton motive force-driven ATP synthesis →	+0.024	+1.138	<.001	<.001	3	14
KIRP	Regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator →	+0.043	+1.395	<.001	<.001	3	13
PAAD	ATP biosynthetic process →	+0.021	+0.304	<.001	.001	2	14
UVM	Positive regulation of chondrocyte proliferation →	+0.080	+1.283	<.001	<.001	3	12
PAAD	Regulation of calcium ion export across plasma membrane →	+0.031	+0.465	<.001	<.001	3	12
THYM	Mitochondrial electron transport, NADH to ubiquinone →	+0.022	+0.577	.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,117 associations by consensus.

Exploration

CHL1-AS2 survival (RNA) · tumor vs normal (RNA) · all CHL1-AS2 data types