CHIT1

Across TCGA patient cohorts, CHIT1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,649 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHIT1-associated genes across cancer lineages are CSF3R, ALOX5AP, and PELATON. Each is linked with CHIT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CHIT1-to-partner and partner-to-CHIT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHIT1 versus CSF3R in PDAC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHIT1→partner) and Y-score (partner→CHIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CSF3R →	+0.982	+1.092	<.001	<.001	3	6
GBM	ALOX5AP →	+1.136	+1.153	<.001	<.001	3	6
CCRCC	PELATON →	+0.710	+0.857	<.001	<.001	3	6
UCEC	VNN3 →	+1.075	+1.013	.005	.001	3	6
GBM	FGR →	+0.885	+1.131	<.001	<.001	3	6
HNSC	NCF1 →	+0.578	+0.773	.004	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,649 associations by consensus.

CHIT1 vs CSF3R — PDAC

Explore this scatter interactively →