CHID1

Across TCGA pan-cancer cohorts, CHID1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CHID1 data layer compared with 23 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CHID1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CHID1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and GBM show a favorable association.

LUAD, GBM, and UCEC are the cancer types where CHID1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	II,III,IV	0.726	0.395	.007	23	view →
GBM	DFS	Median	All	0.506	0.244	.002	11	view →
UCEC	DFS	Median	II,III,IV	0.532	0.869	.035	4	view →
HNSC	DFS	Tertile	II,III,IV	0.881	0.989	.039	1	view →
LSCC	DFS	Median	All	0.929	0.615	.025	1	view →
CCRCC	DFS	Median	All	0.804	0.655	.036	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CHID1–LUAD (OS)

Open the LUAD breakdown →