CHID1

Across TCGA pan-cancer cohorts, CHID1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CHID1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CHID1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CHID1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

COAD, STAD, and LIHC are the cancer types where CHID1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CHID1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	III,IV	+1.038	<.001	11	view →
STAD	Male	III,IV	+0.968	<.001	9	view →
LIHC	Male	All	+0.712	<.001	8	view →
LUAD	Female	All	+0.446	<.001	7	view →
LUSC	Female	All	+0.576	<.001	6	view →
HNSC	All	All	+0.395	.001	6	view →
KIRC	Female	III,IV	+0.377	<.001	6	view →
KICH	All	All	−0.416	.002	5	view →
CHOL	All	All	+0.893	<.001	3	view →
THCA	All	All	+0.166	.018	3	view →
PAAD	All	All	+0.457	.035	2	view →
THCA	Male	IV	−0.266	.008	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 11 lineages.

CHID1–COAD

Open the COAD breakdown →