Across TCGA patient cohorts, CHIC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,997 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CHIC1-associated proteins across cancer lineages are VEZF1, CEBPB, and HMGN5. Each is linked with CHIC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CHIC1-to-partner and partner-to-CHIC1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHIC1→partner) and Y-score (partner→CHIC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	VEZF1 →	+0.360	+0.533	<.001	<.001	3	5
BRCA	CEBPB →	-0.404	-0.632	<.001	<.001	3	4
GBM	HMGN5 →	+0.641	+0.458	.001	.001	2	5
HNSC	CASP4 →	-0.472	-0.561	<.001	.006	3	4
HNSC	UPP1 →	-0.861	-0.576	<.001	.001	3	4
BRCA	TCEAL4 →	+0.537	+0.646	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,997 associations by consensus.

Exploration

CHIC1 survival (RNA) · tumor vs normal (RNA) · all CHIC1 data types