Across TCGA patient cohorts, CHIC1 mutation is significantly associated with the RNA expression of many other genes, with 2,523 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHIC1-associated genes across cancer lineages are CTBP2P10, LINC00265-2P, and MIR4726. Each is linked with CHIC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHIC1-to-partner and partner-to-CHIC1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHIC1→partner) and Y-score (partner→CHIC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CTBP2P10 →	+0.024	+7.741	<.001	.009	3	2
UCEC	LINC00265-2P →	+0.043	+2.446	<.001	.003	3	2
BRCA	MIR4726 →	+0.712	+6.382	<.001	.001	3	1
BRCA	MIR7159 →	+0.620	+5.317	<.001	.006	3	1
BRCA	MIR3118-3 →	+0.371	+7.471	<.001	.008	3	1
BRCA	FAM230A →	+0.029	+7.038	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,523 associations by consensus.

Exploration

CHIC1 survival (RNA) · tumor vs normal (RNA) · all CHIC1 data types