CHI3L1

Across TCGA patient cohorts, CHI3L1 protein abundance is significantly associated with the protein abundance of many other proteins, with 26,675 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CHI3L1-associated proteins across cancer lineages are ARG1, BPI, and AMPD3. Each is linked with CHI3L1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CHI3L1-to-partner and partner-to-CHI3L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHI3L1 versus ARG1 in PDAC, with a Pearson correlation of 0.76.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHI3L1→partner) and Y-score (partner→CHI3L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ARG1 →	+1.007	+0.964	<.001	<.001	3	8
PDAC	BPI →	+1.361	+0.933	<.001	<.001	3	8
UCEC	AMPD3 →	+0.450	+0.725	<.001	.001	3	8
UCEC	RETN →	+1.425	+0.699	<.001	.002	3	8
PDAC	S100A12 →	+1.418	+0.969	<.001	<.001	3	8
PDAC	SERPINB10 →	+1.078	+0.897	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,675 associations by consensus.

CHI3L1 vs ARG1 — PDAC

Explore this scatter interactively →