CHGB

Across TCGA patient cohorts, CHGB RNA expression is significantly associated with the protein abundance of many other proteins, with 12,430 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHGB-associated proteins across cancer lineages are CHGB_S130, GNB5, and CHGA. Each is linked with CHGB in more than 5 cancer types. Because this analysis shows association rather than direction, both CHGB-to-partner and partner-to-CHGB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHGB versus CHGB_S130 in HNSC, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHGB→partner) and Y-score (partner→CHGB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CHGB_S130 →	+1.608	+2.177	<.001	<.001	3	6
GBM	GNB5 →	+0.432	+0.920	<.001	<.001	3	4
PDAC	CHGA →	+0.910	+2.079	<.001	<.001	3	4
HNSC	CHGB_S391 →	+1.680	+2.548	<.001	<.001	3	4
PDAC	CHGB_S405 →	+1.237	+2.448	<.001	<.001	3	4
GBM	HSPA12A →	+0.672	+1.038	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,430 associations by consensus.

CHGB vs CHGB_S130 — HNSC

Explore this scatter interactively →