CHGB

Across TCGA patient cohorts, CHGB protein abundance is significantly associated with the RNA expression of many other genes, with 10,026 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHGB-associated genes across cancer lineages are CHGA, SLC4A10, and SVOP. Each is linked with CHGB in more than 3 cancer types. Because this analysis shows association rather than direction, both CHGB-to-partner and partner-to-CHGB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHGB versus CHGA in GBM, with a Pearson correlation of 0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHGB→partner) and Y-score (partner→CHGB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CHGA →	+2.479	+1.305	<.001	<.001	3	4
GBM	SLC4A10 →	+1.064	+0.784	<.001	<.001	3	3
GBM	SVOP →	+1.503	+1.292	<.001	<.001	3	3
GBM	NAP1L5 →	+0.626	+0.740	<.001	<.001	3	3
GBM	VSTM2A-OT1 →	+0.692	+0.955	.003	<.001	3	3
GBM	LINC02495 →	+0.386	+0.846	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,026 associations by consensus.

CHGB vs CHGA — GBM

Explore this scatter interactively →