CHGB

Across TCGA cell cohorts, CHGB RNA expression is significantly associated with the go_rna of many other GO terms, with 2,026 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CHGB-associated GO terms across cancer lineages are Regulation of myoblast fusion, Establishment of protein localization to organelle, and Mitochondrial electron transport, cytochrome c to oxygen. Each is linked with CHGB in more than 12 cancer types. Because this analysis shows association rather than direction, both CHGB-to-partner and partner-to-CHGB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by CHGB-low versus CHGB-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHGB→partner) and Y-score (partner→CHGB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of myoblast fusion →	+0.103	+2.773	.002	.002	2	13
OESOPHAGUS	Establishment of protein localization to organelle →	+0.062	+0.839	<.001	.004	3	11
LUNG_NSCLC_LUSC	Mitochondrial electron transport, cytochrome c to oxygen →	+0.071	+2.578	.001	.005	3	11
SKIN	Oxidative phosphorylation →	+0.055	+0.771	<.001	<.001	3	10
BLOOD_Lymphoma	Negative regulation of myoblast fusion →	+0.092	+0.895	<.001	.008	2	10
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.112	+2.792	.001	.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,026 associations by consensus.

Regulation of myoblast fusion by CHGB expression — LUNG_SCLC

Explore this box plot interactively →