CHERP

Across TCGA patient cohorts, CHERP RNA expression is significantly associated with the protein abundance of many other proteins, with 15,388 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHERP-associated proteins across cancer lineages are RBBP5, RBBP6_S772, and POLR2E. Each is linked with CHERP in more than 4 cancer types. Because this analysis shows association rather than direction, both CHERP-to-partner and partner-to-CHERP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHERP versus RBBP5 in GBM, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHERP→partner) and Y-score (partner→CHERP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RBBP5 →	+0.360	+0.559	<.001	<.001	3	5
PDAC	RBBP6_S772 →	+0.732	+0.297	<.001	<.001	3	5
GBM	POLR2E →	+0.269	+0.644	<.001	<.001	3	5
OV	SNRPD3 →	+0.283	+1.135	.002	.001	3	5
BRCA	BRD4 →	+0.311	+0.698	<.001	<.001	3	5
GBM	ADNP →	+0.405	+0.582	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,388 associations by consensus.

CHERP vs RBBP5 — GBM

Explore this scatter interactively →