Q-omics provides the consensus-scored CHEK2P1 profile across patient tissues and cancer cell-line models. CHEK2P1 expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in BRCA. Additionally, CHEK2P1 RNA expression shows 4,757 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight BRCA, and STAD as cancer lineages where CHEK2P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes CHEK2P1 survival associations across molecular data types. CHEK2P1 RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

CHEK2P1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	11	BRCA (120)	view →

This table ranks reproducible CHEK2P1 RNA expression–survival associations across cancer types. High CHEK2P1 expression shows unfavorable associations in BRCA, STAD, CESC and PCPG, but favorable associations in HNSC and ESCA. The BRCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify BRCA as the clearest survival context for CHEK2P1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Tertile	All	0.726	0.965	<.001	120	view →
HNSC	DFS	Tertile	All	0.843	0.593	.021	54	view →
STAD	OS	Tertile	All	0.154	0.584	.002	45	view →
CESC	OS	Tertile	III,IV	0.167	0.669	.012	36	view →
ESCA	OS	Tertile	III,IV	0.776	0.345	.013	36	view →
PCPG	OS	Tertile	All	0.524	0.975	<.001	36	view →

Pink = unfavorable, green = favorable. all 11 lineages →

CHEK2P1-BRCA (OS)

Kaplan–Meier survival curve for CHEK2P1 RNA expression in BRCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with CHEK2P1 in patient tissues and cancer cell lines. In patient samples, CHEK2P1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	4,757	STAD (4128)	view →
RNA	2,805	LIHC (619)	view →