CHD7

Across TCGA patient cohorts, CHD7 protein abundance is significantly associated with the protein abundance of many other proteins, with 18,461 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHD7-associated proteins across cancer lineages are ADNP_S98, UBR5, and CKAP2. Each is linked with CHD7 in more than 6 cancer types. Because this analysis shows association rather than direction, both CHD7-to-partner and partner-to-CHD7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHD7 versus ADNP_S98 in BRCA, with a Pearson correlation of 0.47.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHD7→partner) and Y-score (partner→CHD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ADNP_S98 →	+0.937	+0.688	<.001	<.001	3	7
COAD	UBR5 →	+0.334	+0.872	<.001	<.001	3	7
BRCA	CKAP2 →	+0.709	+0.527	<.001	<.001	3	7
GBM	KIFC1 →	+0.491	+0.398	<.001	<.001	3	7
LUAD	CCNB1 →	+1.063	+0.557	<.001	<.001	3	6
BRCA	TOP2A →	+0.823	+0.774	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,461 associations by consensus.

CHD7 vs ADNP_S98 — BRCA

Explore this scatter interactively →