CHD5

Across TCGA patient cohorts, CHD5 protein abundance is significantly associated with the protein abundance of many other proteins, with 6,695 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHD5-associated proteins across cancer lineages are ACIN1_S815, ATG2B, and BACE1. Each is linked with CHD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHD5-to-partner and partner-to-CHD5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHD5 versus ACIN1_S815 in GBM, with a Pearson correlation of -0.52.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHD5→partner) and Y-score (partner→CHD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ACIN1_S815 →	-0.649	-0.452	.002	.003	3	1
GBM	ATG2B →	+0.281	+0.636	<.001	.002	3	1
GBM	BACE1 →	+0.610	+0.553	<.001	<.001	3	1
GBM	BOD1L1_S3019 →	-0.429	-0.481	.001	.001	3	1
GBM	BRCA2 →	+0.571	+0.679	.001	<.001	3	1
GBM	BRSK1_S587 →	+0.576	+0.602	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,695 associations by consensus.

CHD5 vs ACIN1_S815 — GBM

Explore this scatter interactively →