CHD3

Across TCGA patient cohorts, CHD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,898 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CHD3-associated proteins across cancer lineages are CHD3_T1569, ISG20, and TRADD. Each is linked with CHD3 in more than 5 cancer types. Because this analysis shows association rather than direction, both CHD3-to-partner and partner-to-CHD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHD3 versus CHD3_T1569 in LSCC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHD3→partner) and Y-score (partner→CHD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CHD3_T1569 →	+0.597	+0.504	<.001	<.001	3	6
BRCA	ISG20 →	-0.582	-0.571	<.001	<.001	3	5
GBM	TRADD →	-0.318	-0.396	<.001	<.001	3	5
HNSC	CHD3_S1605 →	+0.522	+0.563	<.001	.002	3	5
LSCC	CHD3_S73 →	+0.806	+0.486	<.001	.001	3	5
PDAC	MPRIP →	+0.258	+0.291	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,898 associations by consensus.

CHD3 vs CHD3_T1569 — LSCC

Explore this scatter interactively →