CHD3

Across TCGA patient cohorts, CHD3 protein abundance is significantly associated with the RNA expression of many other genes, with 15,146 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHD3-associated genes across cancer lineages are RPAIN, NCBP3, and PATZ1. Each is linked with CHD3 in more than 5 cancer types. Because this analysis shows association rather than direction, both CHD3-to-partner and partner-to-CHD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHD3 versus RPAIN in BRCA, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHD3→partner) and Y-score (partner→CHD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPAIN →	+0.730	+0.438	<.001	<.001	3	6
BRCA	NCBP3 →	+0.451	+0.348	<.001	.001	3	6
BRCA	PATZ1 →	+0.834	+0.399	<.001	<.001	3	5
HNSC	CPSF6 →	+0.777	+0.537	<.001	<.001	3	5
HNSC	TTC19 →	+0.549	+0.317	.002	.001	3	5
BRCA	CHST10 →	+0.697	+0.261	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,146 associations by consensus.

CHD3 vs RPAIN — BRCA

Explore this scatter interactively →