CHD3

Across TCGA cell cohorts, CHD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,602 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CHD3-associated GO terms across cancer lineages are Regulation of cell fate specification, Nucleic acid transport, and RNA transport. Each is linked with CHD3 in more than 17 cancer types. Because this analysis shows association rather than direction, both CHD3-to-partner and partner-to-CHD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell fate specification grouped by CHD3-low versus CHD3-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHD3→partner) and Y-score (partner→CHD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of cell fate specification →	+0.147	+0.988	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Nucleic acid transport →	+0.113	+1.365	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	RNA transport →	+0.113	+1.365	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Establishment of RNA localization →	+0.120	+1.395	<.001	<.001	3	15
BREAST	Negative regulation of calcium ion export across plasma membrane →	+0.082	+1.027	.001	<.001	3	15
OESOPHAGUS	Regulation of transcription initiation by RNA polymerase II →	+0.071	+1.162	.007	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,602 associations by consensus.

Regulation of cell fate specification by CHD3 expression — BLOOD_Lymphoma

Explore this box plot interactively →