CHD1L

Across TCGA patient cohorts, CHD1L protein abundance is significantly associated with the RNA expression of many other genes, with 15,822 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHD1L-associated genes across cancer lineages are COG2, UCK2, and MAP3K21. Each is linked with CHD1L in more than 5 cancer types. Because this analysis shows association rather than direction, both CHD1L-to-partner and partner-to-CHD1L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHD1L versus COG2 in UCEC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHD1L→partner) and Y-score (partner→CHD1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	COG2 →	+0.427	+0.271	<.001	<.001	3	6
LSCC	UCK2 →	+0.762	+0.393	<.001	<.001	3	6
LSCC	MAP3K21 →	+0.855	+0.454	<.001	<.001	3	6
UCEC	CHTOP →	+0.419	+0.307	<.001	<.001	3	6
LSCC	FLVCR1 →	+0.795	+0.460	<.001	<.001	3	6
BRCA	POLR3C →	+0.649	+0.403	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,822 associations by consensus.

CHD1L vs COG2 — UCEC

Explore this scatter interactively →