CHD1L

Across TCGA cell cohorts, CHD1L mutation is significantly associated with the RNA expression of many other genes, with 193 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CHD1L-associated genes across cancer lineages are COL9A1, NPHS2, and OR10H2. Each is linked with CHD1L in more than 1 cancer types. Because this analysis shows association rather than direction, both CHD1L-to-partner and partner-to-CHD1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COL9A1 grouped by CHD1L-low versus CHD1L-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHD1L→partner) and Y-score (partner→CHD1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	COL9A1 →	+0.319	+3.115	.001	.005	3	1
URINARY_TRACT	NPHS2 →	+0.125	+3.459	.003	.002	3	1
URINARY_TRACT	OR10H2 →	+0.036	+3.459	<.001	.002	3	1
LUNG_SCLC	REG3A →	+0.073	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	OR2D2 →	+0.051	+4.115	<.001	.003	3	1
BLOOD_Lymphoma	OR2AT4 →	+0.010	+4.070	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 193 associations by consensus.

COL9A1 by CHD1L expression — URINARY_TRACT

Explore this box plot interactively →