CHCHD7

Across TCGA patient cohorts, CHCHD7 protein abundance is significantly associated with the RNA expression of many other genes, with 4,555 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHCHD7-associated genes across cancer lineages are FAHD2A, FANCL, and ALMS1. Each is linked with CHCHD7 in more than 2 cancer types. Because this analysis shows association rather than direction, both CHCHD7-to-partner and partner-to-CHCHD7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHCHD7 versus FAHD2A in OV, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHCHD7→partner) and Y-score (partner→CHCHD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FAHD2A →	-0.641	-0.858	<.001	<.001	3	3
LSCC	FANCL →	-0.494	-0.216	.002	.002	3	3
OV	ALMS1 →	-0.499	-0.423	.005	.006	3	3
OV	SEMA4F →	-0.877	-0.889	<.001	<.001	3	3
LSCC	VANGL2 →	-0.903	-0.211	.001	.002	3	3
OV	ZNF519 →	-0.494	-0.767	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,555 associations by consensus.

CHCHD7 vs FAHD2A — OV

Explore this scatter interactively →