CHCHD7

Across TCGA cell cohorts, CHCHD7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,848 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CHCHD7-associated GO terms across cancer lineages are Peroxisome fission, Regulation of humoral immune response, and Interleukin-9-mediated signaling pathway. Each is linked with CHCHD7 in more than 6 cancer types. Because this analysis shows association rather than direction, both CHCHD7-to-partner and partner-to-CHCHD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peroxisome fission grouped by CHCHD7-low versus CHCHD7-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHCHD7→partner) and Y-score (partner→CHCHD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Peroxisome fission →	+0.086	+0.543	.001	.008	2	7
BONE	Regulation of humoral immune response →	-0.290	-1.700	<.001	<.001	3	6
BLOOD_Lymphoma	Interleukin-9-mediated signaling pathway →	-0.185	-0.907	<.001	<.001	3	6
BLOOD_Leukemia	Cardiac muscle cell differentiation →	-0.061	-0.619	<.001	<.001	3	6
BONE	Glycosylceramide metabolic process →	-0.165	-1.494	.001	.004	3	6
BLOOD_Leukemia	Regulation of establishment of protein localization to chromosome →	+0.076	+0.894	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,848 associations by consensus.

Peroxisome fission by CHCHD7 expression — PANCREAS

Explore this box plot interactively →