CHCHD4

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CHCHD4 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CHCHD4-associated genes across cancer lineages are CD300H. Each is linked with CHCHD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHCHD4-to-partner and partner-to-CHCHD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300H grouped by CHCHD4-low versus CHCHD4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHCHD4→partner) and Y-score (partner→CHCHD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINECD300H →+0.045+5.415<.001.00431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD300H by CHCHD4 expression — LARGE_INTESTINE

Box plot of CD300H in CHCHD4-low vs CHCHD4-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration