CHCHD3P2

Across TCGA pan-cancer cohorts, CHCHD3P2 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated CHCHD3P2 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher CHCHD3P2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CHCHD3P2 expression acts as an unfavorable survival marker, although some lineages such as SKCM and KIRC show a favorable association.

UCS, READ, and UVM are the cancer types where CHCHD3P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	All	0.068	0.524	<.001	144	view →
READ	DFS	Tertile	All	0.193	0.824	<.001	63	view →
UVM	DFS	Tertile	All	0.079	0.746	<.001	54	view →
ESCA	OS	Tertile	II,III,IV	0.103	0.868	<.001	54	view →
CHOL	DFS	Tertile	All	0.045	0.486	.009	45	view →
THCA	DFS	Tertile	All	0.062	0.811	<.001	45	view →
STAD	OS	Tertile	IV	0.124	0.508	.007	36	view →
MESO	OS	Tertile	All	0.018	0.559	<.001	36	view →
LUSC	OS	Tertile	All	0.231	0.662	.003	27	view →
LUAD	OS	Tertile	All	0.329	0.676	.024	18	view →
BLCA	DFS	Tertile	III,IV	0.078	0.489	<.001	9	view →
SKCM	OS	Tertile	All	0.698	0.309	.035	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

CHCHD3P2–UCS (DFS)

Open the UCS breakdown →