CHCHD3P2

Across TCGA pan-cancer cohorts, CHCHD3P2 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of CHCHD3P2’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CHCHD3P2 RNA is repressed in tumor relative to normal tissue. In most cancer types CHCHD3P2 is over-expressed in tumor, although a few such as COAD and BRCA show the opposite, repressed pattern.

COAD, BRCA, and LUSC are the cancer types where CHCHD3P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CHCHD3P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	−0.025	.036	2	view →
BRCA	All	III,IV	−0.016	.045	2	view →
LUSC	All	All	−0.020	.019	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

CHCHD3P2–COAD

Open the COAD breakdown →