CHCHD3

Across TCGA patient cohorts, CHCHD3 protein abundance is significantly associated with the RNA expression of many other genes, with 14,732 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHCHD3-associated genes across cancer lineages are SERPINF1, C1R, and LILRB3. Each is linked with CHCHD3 in more than 5 cancer types. Because this analysis shows association rather than direction, both CHCHD3-to-partner and partner-to-CHCHD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHCHD3 versus SERPINF1 in OV, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHCHD3→partner) and Y-score (partner→CHCHD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SERPINF1 →	-1.841	-0.495	<.001	<.001	3	6
OV	C1R →	-1.001	-0.308	.001	.008	3	6
COAD	LILRB3 →	-0.854	-0.254	<.001	<.001	3	6
COAD	VGLL3 →	-0.975	-0.351	<.001	<.001	3	6
OV	RCN3 →	-0.932	-0.287	<.001	<.001	3	6
GBM	MS4A4A →	-1.142	-0.270	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,732 associations by consensus.

CHCHD3 vs SERPINF1 — OV

Explore this scatter interactively →