CHCHD3

Across TCGA cell cohorts, CHCHD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,199 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CHCHD3-associated GO terms across cancer lineages are Positive regulation of cell cycle phase transition, Spindle elongation, and DNA-templated transcription termination. Each is linked with CHCHD3 in more than 12 cancer types. Because this analysis shows association rather than direction, both CHCHD3-to-partner and partner-to-CHCHD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell cycle phase transition grouped by CHCHD3-low versus CHCHD3-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHCHD3→partner) and Y-score (partner→CHCHD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of cell cycle phase transition →	+0.105	+1.375	<.001	<.001	3	13
SOFT_TISSUE	Spindle elongation →	+0.233	+0.878	.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription termination →	+0.108	+0.847	<.001	.001	3	13
SOFT_TISSUE	Positive regulation of mitotic cell cycle phase transition →	+0.129	+0.763	<.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Defense response to bacterium →	-0.121	-0.694	.001	.002	3	12
SOFT_TISSUE	Positive regulation of cell cycle →	+0.082	+0.763	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,199 associations by consensus.

Positive regulation of cell cycle phase transition by CHCHD3 expression — PANCREAS

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