CHCHD2P6

Across TCGA pan-cancer cohorts, CHCHD2P6 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated CHCHD2P6 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CHCHD2P6 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CHCHD2P6 expression acts as an unfavorable survival marker, although some lineages such as KIRC and PAAD show a favorable association.

KIRC, PAAD, and SKCM are the cancer types where CHCHD2P6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.702	0.541	<.001	79	view →
PAAD	OS	Median	All	0.549	0.248	<.001	39	view →
SKCM	OS	Quartile	II,III,IV	0.887	0.586	<.001	38	view →
ACC	DFS	Quartile	All	0.211	0.788	<.001	26	view →
LGG	DFS	Median	All	0.784	0.878	<.001	23	view →
KICH	OS	Quartile	II,III,IV	0.547	1.000	.023	18	view →
UCS	DFS	Tertile	All	0.420	0.136	.015	18	view →
KIRP	OS	Tertile	III,IV	1.000	0.270	.012	15	view →
BLCA	DFS	Tertile	III,IV	0.526	0.676	.011	12	view →
LIHC	OS	Tertile	All	0.691	0.841	.009	10	view →
UVM	DFS	Tertile	III,IV	0.244	0.651	.020	10	view →
CHOL	DFS	Tertile	All	0.099	0.584	.031	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

CHCHD2P6–KIRC (DFS)

Open the KIRC breakdown →