CHCHD1

Across TCGA patient cohorts, CHCHD1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,619 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHCHD1-associated genes across cancer lineages are COX5A, ADAMTS10, and MCRIP2. Each is linked with CHCHD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CHCHD1-to-partner and partner-to-CHCHD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHCHD1 versus COX5A in UCEC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHCHD1→partner) and Y-score (partner→CHCHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	COX5A →	+0.607	+0.352	.006	<.001	3	4
LUAD	ADAMTS10 →	-0.468	-0.206	<.001	<.001	3	4
OV	MCRIP2 →	+0.508	+0.446	<.001	.002	3	4
BRCA	FOLR2 →	-1.105	-0.281	<.001	.006	3	4
OV	WTIP →	-0.789	-0.427	<.001	.004	3	3
OV	FXYD7 →	-0.900	-0.488	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,619 associations by consensus.

CHCHD1 vs COX5A — UCEC

Explore this scatter interactively →