CHAF1A

Across TCGA patient cohorts, CHAF1A RNA expression is significantly associated with the protein abundance of many other proteins, with 23,930 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHAF1A-associated proteins across cancer lineages are LIG1, MCM2, and MCM3. Each is linked with CHAF1A in more than 9 cancer types. Because this analysis shows association rather than direction, both CHAF1A-to-partner and partner-to-CHAF1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHAF1A versus LIG1 in LSCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHAF1A→partner) and Y-score (partner→CHAF1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LIG1 →	+0.505	+0.897	<.001	<.001	3	10
LUAD	MCM2 →	+0.798	+0.815	<.001	<.001	3	10
LUAD	MCM3 →	+0.822	+0.797	<.001	<.001	3	10
LUAD	MCM4 →	+0.851	+0.800	<.001	<.001	3	10
LUAD	MCM5 →	+0.763	+0.800	<.001	<.001	3	10
LUAD	MCM6 →	+0.816	+0.800	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,930 associations by consensus.

CHAF1A vs LIG1 — LSCC

Explore this scatter interactively →