CHAF1A

Across TCGA patient cohorts, CHAF1A protein abundance is significantly associated with the RNA expression of many other genes, with 16,687 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHAF1A-associated genes across cancer lineages are MYBL2, CDCA3, and CENPA. Each is linked with CHAF1A in more than 8 cancer types. Because this analysis shows association rather than direction, both CHAF1A-to-partner and partner-to-CHAF1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHAF1A versus MYBL2 in LUAD, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHAF1A→partner) and Y-score (partner→CHAF1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MYBL2 →	+1.550	+0.385	<.001	<.001	3	9
OV	CDCA3 →	+0.992	+0.512	.002	.003	3	9
UCEC	CENPA →	+1.136	+0.538	<.001	<.001	3	9
GBM	KIF14 →	+1.105	+0.556	<.001	<.001	3	9
UCEC	CDCA8 →	+1.168	+0.604	<.001	<.001	3	9
OV	TROAP →	+1.374	+0.661	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,687 associations by consensus.

CHAF1A vs MYBL2 — LUAD

Explore this scatter interactively →