CHADL

Across TCGA patient cohorts, CHADL RNA expression is significantly associated with the protein abundance of many other proteins, with 18,547 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHADL-associated proteins across cancer lineages are SND1, TRIM2, and DDAH1. Each is linked with CHADL in more than 5 cancer types. Because this analysis shows association rather than direction, both CHADL-to-partner and partner-to-CHADL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHADL versus SND1 in BRCA, with a Pearson correlation of -0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHADL→partner) and Y-score (partner→CHADL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SND1 →	-0.308	-0.904	<.001	<.001	3	6
LSCC	TRIM2 →	+0.676	+0.557	<.001	<.001	3	6
BRCA	DDAH1 →	+0.702	+0.824	<.001	<.001	3	6
GBM	RPS13 →	-0.328	-1.446	<.001	<.001	3	5
PDAC	RPS2 →	-0.280	-0.468	<.001	<.001	3	5
GBM	RPS24 →	-0.459	-1.859	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,547 associations by consensus.

CHADL vs SND1 — BRCA

Explore this scatter interactively →