CHADL

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CHADL protein abundance is significantly associated with the protein abundance of many other proteins, with 4,295 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHADL-associated proteins across cancer lineages are TNRC18_S1136, COMMD9, and GART. Each is linked with CHADL in more than 1 cancer types. Because this analysis shows association rather than direction, both CHADL-to-partner and partner-to-CHADL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHADL versus TNRC18_S1136 in HNSC, with a Pearson correlation of -0.70.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHADL→partner) and Y-score (partner→CHADL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCTNRC18_S1136 →-1.821-0.895<.001<.00132
HNSCCOMMD9 →-0.425-0.722<.001<.00132
HNSCGART →-0.332-0.917.004.00132
HNSCHECW2 →+0.413+0.635<.001<.00132
GBMNPM1 →-0.326-0.387.001<.00132
HNSCPPIL4_S178 →-0.493-0.786<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,295 associations by consensus.

CHADL vs TNRC18_S1136 — HNSC

Per-sample scatter of CHADL vs TNRC18_S1136 in HNSC (Pearson r = -0.70).

Explore this scatter interactively →

Exploration