CHADL

Across TCGA cell cohorts, CHADL RNA expression is significantly associated with the go_rna of many other GO terms, with 2,582 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible CHADL-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with CHADL in more than 9 cancer types. Because this analysis shows association rather than direction, both CHADL-to-partner and partner-to-CHADL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by CHADL-low versus CHADL-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHADL→partner) and Y-score (partner→CHADL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of myoblast fusion →	+0.119	+0.526	<.001	<.001	3	10
OVARY	Regulation of myoblast fusion →	+0.107	+0.526	<.001	<.001	3	9
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.111	+0.526	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of type I interferon-mediated signaling pathway →	+0.130	+0.635	.003	.002	3	9
OESOPHAGUS	Spliceosomal tri-snRNP complex assembly →	+0.089	+0.432	.001	.004	3	8
OESOPHAGUS	Regulatory ncRNA-mediated gene silencing →	+0.067	+0.446	.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,582 associations by consensus.

Negative regulation of myoblast fusion by CHADL expression — OVARY

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