CHAC2

Across TCGA patient cohorts, CHAC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,771 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHAC2-associated proteins across cancer lineages are KPNA2, SMC4, and UTP4. Each is linked with CHAC2 in more than 8 cancer types. Because this analysis shows association rather than direction, both CHAC2-to-partner and partner-to-CHAC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHAC2 versus KPNA2 in BRCA, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHAC2→partner) and Y-score (partner→CHAC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KPNA2 →	+0.626	+0.743	<.001	<.001	3	9
OV	SMC4 →	+0.539	+0.984	<.001	<.001	3	8
LSCC	UTP4 →	+0.371	+0.772	<.001	<.001	3	7
OV	NCAPG_S674 →	+1.665	+1.260	<.001	<.001	3	7
LSCC	PSME4 →	+0.331	+0.700	<.001	<.001	3	7
LSCC	TK1 →	+0.515	+0.672	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,771 associations by consensus.

CHAC2 vs KPNA2 — BRCA

Explore this scatter interactively →