CH25H

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CH25H Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CH25H data layer compared with 25 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CH25H Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CH25H expression acts as an unfavorable survival marker.

LUAD and SKCM are the cancer types where CH25H Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADDFSMedianIV0.3420.893<.0016view →
SKCMDFSMedianIV0.0360.433<.0016view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CH25H–LUAD (DFS)

Kaplan–Meier survival curve for CH25H mutant vs wild-type samples in LUAD.

Open the LUAD breakdown →

Exploration