CGREF1

Across TCGA patient cohorts, CGREF1 mutation is significantly associated with the RNA expression of many other genes, with 1,080 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CGREF1-associated genes across cancer lineages are RN7SL248P, ZNF77, and VWC2L-IT1. Each is linked with CGREF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CGREF1-to-partner and partner-to-CGREF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by CGREF1-low versus CGREF1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CGREF1→partner) and Y-score (partner→CGREF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.072	+3.500	<.001	.002	3	2
UCEC	ZNF77 →	+0.473	+2.254	.002	.006	3	2
COAD	VWC2L-IT1 →	+0.164	+5.721	.001	.001	3	2
COAD	LIN28AP2 →	+0.166	+5.251	<.001	.003	3	2
COAD	SNRPCP20 →	+0.684	+4.831	<.001	.003	3	2
UCEC	RNU6-1318P →	+0.313	+2.658	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,080 associations by consensus.

RN7SL248P by CGREF1 expression — UCEC

Explore this box plot interactively →