CGNL1

Across TCGA cell cohorts, CGNL1 mutation is significantly associated with the RNA expression of many other genes, with 207 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CGNL1-associated genes across cancer lineages are SERPINB11, OR10AG1, and PNLIPRP3. Each is linked with CGNL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CGNL1-to-partner and partner-to-CGNL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SERPINB11 grouped by CGNL1-low versus CGNL1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CGNL1→partner) and Y-score (partner→CGNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	SERPINB11 →	+0.601	+3.637	<.001	.002	3	2
OVARY	OR10AG1 →	+0.020	+5.807	<.001	.001	3	2
BLOOD_Leukemia	PNLIPRP3 →	+0.008	+2.966	<.001	.005	3	2
OESOPHAGUS	IL17F →	+0.030	+3.158	.001	.001	3	1
OESOPHAGUS	HBG1 →	+0.111	+2.845	<.001	.005	3	1
SOFT_TISSUE	TSPY3 →	+0.033	+3.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 207 associations by consensus.

SERPINB11 by CGNL1 expression — SOFT_TISSUE

Explore this box plot interactively →