Across TCGA patient cohorts, CGB5 mutation is significantly associated with the RNA expression of many other genes, with 297 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CGB5-associated genes across cancer lineages are FAM236D, NT5C1B-RDH14, and RNU6-222P. Each is linked with CGB5 in more than 2 cancer types. Because this analysis shows association rather than direction, both CGB5-to-partner and partner-to-CGB5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CGB5→partner) and Y-score (partner→CGB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	FAM236D →	+0.203	+5.274	<.001	.006	3	3
SKCM	NT5C1B-RDH14 →	+0.055	+4.475	<.001	.005	3	2
UCEC	RNU6-222P →	+0.714	+3.224	<.001	.004	3	2
UCEC	RNU6-221P →	+0.458	+4.660	<.001	.003	3	2
STAD	RN7SKP159 →	+0.197	+5.274	.002	.006	3	2
STAD	XKRYP3 →	+0.098	+6.070	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 297 associations by consensus.

Exploration

CGB5 survival (RNA) · tumor vs normal (RNA) · all CGB5 data types