CGB2

Across TCGA patient cohorts, CGB2 protein abundance is significantly associated with the protein abundance of many other proteins, with 67 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CGB2-associated proteins across cancer lineages are NES_S1590, SEC24A, and SIPA1L1_S1528. Each is linked with CGB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CGB2-to-partner and partner-to-CGB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CGB2 versus NES_S1590 in LUAD, with a Pearson correlation of -0.90.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CGB2→partner) and Y-score (partner→CGB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NES_S1590 →	-1.359	-1.196	<.001	.008	2	1
LUAD	SEC24A →	+0.600	+1.519	.008	.009	1	1
LUAD	SIPA1L1_S1528 →	+0.850	+0.894	.009	.007	1	1
LUAD	SIPA1L2_S1549 →	-1.444	-1.366	.008	.009	1	1
LUAD	SMARCAD1_S132 →	-0.414	-1.009	.006	.003	1	1
LUAD	SPAST_S268 →	-1.690	-1.196	.003	.008	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 67 associations by consensus.

CGB2 vs NES_S1590 — LUAD

Explore this scatter interactively →