CGB2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CGB2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CGB2-associated genes across cancer lineages are Keratinocytes and Sebocytes. Each is linked with CGB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CGB2-to-partner and partner-to-CGB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Keratinocytes grouped by CGB2-low versus CGB2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CGB2→partner) and Y-score (partner→CGB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECKeratinocytes →-0.017-2.871.038.03911
UCECSebocytes →-0.038-2.978.008.03711
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Keratinocytes by CGB2 expression — UCEC

Box plot of Keratinocytes in CGB2-low vs CGB2-high samples in UCEC.

Explore this box plot interactively →

Exploration