CGA

Across TCGA pan-cancer cohorts, CGA Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CGA data layer compared with 22 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher CGA Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CGA expression acts as an unfavorable survival marker.

READ and GBM are the cancer types where CGA Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Median	II,III,IV	0.054	0.934	<.001	18	view →
GBM	OS	Median	All	0.058	0.416	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CGA–READ (OS)

Open the READ breakdown →