CFHR1

Across TCGA patient cohorts, CFHR1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,344 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CFHR1-associated genes across cancer lineages are ACTA2, FGF7, and TAGLN. Each is linked with CFHR1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CFHR1-to-partner and partner-to-CFHR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CFHR1 versus ACTA2 in BRCA, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFHR1→partner) and Y-score (partner→CFHR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ACTA2 →	+1.087	+0.746	.002	<.001	3	6
BRCA	FGF7 →	+1.242	+0.798	<.001	<.001	3	6
GBM	TAGLN →	+1.119	+0.615	<.001	<.001	3	6
GBM	IGFBP7 →	+0.771	+0.470	<.001	.001	3	5
GBM	LYVE1 →	+1.523	+0.586	<.001	<.001	3	5
UCEC	MYL9 →	+1.029	+0.608	.001	.006	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,344 associations by consensus.

CFHR1 vs ACTA2 — BRCA

Explore this scatter interactively →