CFHR1

Across TCGA cell cohorts, CFHR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,052 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CFHR1-associated GO terms across cancer lineages are Neuroblast differentiation, Chloride transmembrane transport, and DNA-templated transcription termination. Each is linked with CFHR1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CFHR1-to-partner and partner-to-CFHR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neuroblast differentiation grouped by CFHR1-low versus CFHR1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CFHR1→partner) and Y-score (partner→CFHR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Neuroblast differentiation →	+1.019	+0.448	<.001	.001	3	6
LUNG_NSCLC_LUAD	Chloride transmembrane transport →	-0.044	-0.737	<.001	.008	3	6
LIVER	DNA-templated transcription termination →	+0.067	+1.294	.004	.007	3	6
CNS	Acetylcholine catabolic process →	+0.873	+0.248	<.001	.003	2	6
LUNG_NSCLC_LUAD	Negative regulation of microtubule polymerization or depolymerization →	+0.070	+0.775	<.001	<.001	3	5
LIVER	Vitamin K metabolic process →	+0.193	+2.255	.002	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,052 associations by consensus.

Neuroblast differentiation by CFHR1 expression — BLOOD_Lymphoma

Explore this box plot interactively →