CFH

Across TCGA patient cohorts, CFH protein abundance is significantly associated with the RNA expression of many other genes, with 16,032 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CFH-associated genes across cancer lineages are COL5A1, CD248, and CALHM5. Each is linked with CFH in more than 8 cancer types. Because this analysis shows association rather than direction, both CFH-to-partner and partner-to-CFH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CFH versus COL5A1 in OV, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFH→partner) and Y-score (partner→CFH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	COL5A1 →	+1.771	+0.481	<.001	<.001	3	9
OV	CD248 →	+1.304	+0.524	<.001	<.001	3	9
OV	CALHM5 →	+0.869	+0.793	<.001	<.001	3	9
BRCA	CD93 →	+0.857	+0.566	<.001	<.001	3	9
COAD	MYL9 →	+0.965	+0.456	<.001	<.001	3	8
COAD	MEDAG →	+1.082	+0.514	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,032 associations by consensus.

CFH vs COL5A1 — OV

Explore this scatter interactively →