CFC1B

Across TCGA patient cohorts, CFC1B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,651 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CFC1B-associated GO terms across cancer lineages are Positive regulation of peptide secretion, Positive regulation of insulin secretion, and Action potential. Each is linked with CFC1B in more than 4 cancer types. Because this analysis shows association rather than direction, both CFC1B-to-partner and partner-to-CFC1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of peptide secretion grouped by CFC1B-low versus CFC1B-high in PAAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CFC1B→partner) and Y-score (partner→CFC1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PAAD	Positive regulation of peptide secretion →	+0.031	+0.138	<.001	<.001	3	5
PAAD	Positive regulation of insulin secretion →	+0.039	+0.145	<.001	<.001	3	4
LGG	Action potential →	+0.023	+0.005	<.001	.008	3	3
PAAD	Regulation of peptide transport →	+0.026	+0.064	<.001	<.001	3	3
PAAD	Negative regulation of G protein-coupled receptor signaling pathway →	+0.029	+0.193	<.001	<.001	3	3
PAAD	Positive regulation of hormone secretion →	+0.027	+0.132	<.001	<.001	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,651 associations by consensus.

Positive regulation of peptide secretion by CFC1B expression — PAAD

Explore this box plot interactively →