CFC1B

Across TCGA pan-cancer cohorts, CFC1B RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated CFC1B data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CFC1B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CFC1B expression acts as an unfavorable survival marker, although some lineages such as PAAD and OV show a favorable association.

KIRC, COAD, and LIHC are the cancer types where CFC1B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.440	0.810	<.001	156	view →
COAD	DFS	Tertile	All	0.197	0.695	<.001	126	view →
LIHC	OS	Tertile	II,III,IV	0.051	0.716	<.001	72	view →
TGCT	DFS	Tertile	II,III,IV	0.015	0.919	<.001	54	view →
SKCM	DFS	Tertile	III,IV	0.087	0.647	.013	36	view →
PAAD	OS	Quartile	All	0.589	0.251	.006	22	view →
SCLC	DFS	Tertile	All	0.192	0.793	.017	18	view →
UVM	OS	Tertile	All	0.292	0.674	.035	18	view →
LUAD	DFS	Tertile	IV	0.448	0.936	<.001	18	view →
THYM	DFS	Median	II,III,IV	0.549	0.857	.008	17	view →
OV	DFS	Tertile	IV	0.818	0.427	.037	6	view →
BRCA	DFS	Tertile	II,III,IV	1.000	0.510	.045	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

CFC1B–KIRC (OS)

Open the KIRC breakdown →