CFC1

Across TCGA patient cohorts, CFC1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFC1-associated genes across cancer lineages are RNA5SP275, HMGB1P42, and MIR6811. Each is linked with CFC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFC1-to-partner and partner-to-CFC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP275 grouped by CFC1-low versus CFC1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFC1→partner) and Y-score (partner→CFC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP275 →	+0.492	+5.444	<.001	.002	3	1
LUAD	HMGB1P42 →	+0.067	+4.712	<.001	.007	3	1
LUAD	MIR6811 →	+0.652	+6.599	<.001	<.001	3	1
UCEC	RNU1-34P →	+0.513	+6.226	<.001	.001	3	1
UCEC	LINC01802 →	+0.205	+5.031	<.001	.009	3	1
UCEC	MTATP6P29 →	+0.735	+5.133	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

RNA5SP275 by CFC1 expression — LUAD

Explore this box plot interactively →